- "Yes, but you have to understand. The bullet entered just above his hip and lodged in his right arm."
- — Doctor to Alexander Hamilton in Stay Alive (Reprise)
Dr. David Hosack was a notable physician and doctor and is most well-known for tending to Philip Hamilton after the young man's duel with George Eacker. Shortly after, he accompanied Alexander Hamilton in his duel with Aaron Burr, where he tended to a mortally wounded Hamilton before he passed away.
- Not shown in the musical is the fact that Hosack saved Philip Hamilton's life from a terrible fever in 1797, thus earning Alexander Hamilton's profound gratitude and trust.